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Thalidomide-O-amido-PEG2-C2-NH2 TFA
CAS No. 1957235-75-4
Thalidomide-O-amido-PEG2-C2-NH2 TFA ( Cereblon Ligand-Linker Conjugates 10 TFA; E3 Ligase Ligand-Linker Conjugates 24 TFA )
产品货号. M26947 CAS No. 1957235-75-4
Thalidomide-O-amido-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥729 | 有现货 |
|
| 10MG | ￥1069 | 有现货 |
|
| 25MG | ￥1798 | 有现货 |
|
| 50MG | ￥2665 | 有现货 |
|
| 100MG | ￥3993 | 有现货 |
|
| 200MG | ￥6043 | 有现货 |
|
| 500MG | ￥14013 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Thalidomide-O-amido-PEG2-C2-NH2 TFA
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Thalidomide-O-amido-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.
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产品描述Thalidomide-O-amido-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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同义词Cereblon Ligand-Linker Conjugates 10 TFA; E3 Ligase Ligand-Linker Conjugates 24 TFA
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通路Others
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靶点Other Targets
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受体H2 receptor
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研究领域——
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适应症——
化学信息
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CAS Number1957235-75-4
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分子量576.5
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分子式C23H27F3N4O10
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纯度>98% (HPLC)
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溶解度——
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SMILESOC(=O)C(F)(F)F.NCCOCCOCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Agut J, Sánchez JC, Sacristán A, Action of ebrotidine, ranitidine and cimetidine on the specific binding to histamine H1- and H2-receptors. Arzneimittelforschung. 1997 Apr;47(4A):447-9.
产品手册
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